Vol.103 No.1 contentsPRACTICA OTO-RHINO-LARYNGOLOGICA
Vol. 103 No. 1 January 2010
A Case of Adenoid Cystic Carcinoma of the Larynx
Akihiro Ishida, Shuji Koike, Takashi Nasu,
Daisuke Noda, Kenichi Ishii and Masaru Aoyagi
(Yamagata University School of Medicine)
Laryngeal adenoid cystic carcinoma is rare disease. We report herein on a case of adenoid cystic carcinoma arising in the subglottic region of the larynx. A 52-year-old female presented with a 2-month history of progressive dyspnea during exercise. Endoscopic examination of the larynx revealed a submucosal mass lesion in the subglottic area. An excisional biopsy was performed using the laryngofissure technique. The pathological diagnosis was cribriform type adenoid cystic carcinoma. The patient underwent total laryngectomy with bilateral neck dissection (Level 2-4) and postoperative radiation therapy. She has been alive without locoregional recurrence and distant metastasis for 18 months.
We discuss herein the clinical and pathological features of adenoid cystic carcinoma of the larynx as well as reviews of the reported cases in the literature. Up to the present, only 22 cases including our case have been reported in Japan. For the patients with adenoid cystic carcinoma of the larynx, long-term follow-up is essential because of the possibility of delayed recurrence or metastases.
Key words :adenoid cystic carcinoma, larynx, subglottic cancer