Vol.103 No.2 contentsPRACTICA OTO-RHINO-LARYNGOLOGICA
Vol. 103 No. 2 February 2010
Experimental Study of Autologous Fibrin Glue Bonding Strength
Yoshihisa Ueda, Yoichi Matsuda, Tomoyuki Kurita,
Shinsuke Ito and Tadashi Nakashima
(Kurume University School of Medicine)
After the novel report of Yuasa et al., simple myringoplasty using commercial fibrin glue has gone into widespread use in Japan. The production of this glue, however, involves blood transfusion, with the risk, at least, of possible unknown viral infection. The autologous fibrin glue now used, however, lacks sufficient bonding power, so we experimentally refined a concentrated cryoprecipitate and examined its bonding strength compared to commercial glue at 5 and 10 minutes after fibrinogen was mixed thrombin. We found it to be much weaker than the commercial product, making it unsuitable for simple myringoplasty and the need for autologous fibrin glue based on higher fibrinogen concentration yet unmet.
Key words :autologous fibrin glue, bonding strength, concentrated cryoprecipitate