Vol.98 No.2 contentsPRACTICA OTO-RHINO-LARYNGOLOGICA
Vol. 98 No. 2 February 2005
The Effect of Combined Treatment with Dilazep Dihydrochloride
and Isosorbide on Hearing Improvement in Lermoyez's Disease
and Meniere's Disease at Advanced Stage
Satoshi Seki, Kenya Inukai, Shinichirou Takahashi and Sugata Takahashi
(Niigata University Faculty of Medicine)
We report 2 cases of Lermoyez's disease and a case of Meniere's disease at advanced stages showing hearing improvement following treatment with a combination of Dilazep dihydrochloride and Isosorbide. It is suggested that this combined treatment is quite effective for Lermoyez's disease, suggesting that Lermoyez's disease is caused by both endolymphatic hydrops and disturbance of vascular circulation. Comparison of the hearing improvements among cases for which this treatment was effective and ineffective indicated that this treatment could be useful not only for Lermoyez's disease but also for Meniere's disease when vertigo is under control in patients whose job is not very busy or stressful.
Key words : Dilazep dihydrochloride, Isosorbide, hearing, Meniere's disease