Vol.99 No.2 contentsPRACTICA OTO-RHINO-LARYNGOLOGICA
Vol. 99 No. 2 February 2006
Clinical Study of Levofloxacin (LVFX) 400 mg Orally in Two Divided Portions
for Acute Exacerbation of Chronic Otitis Media and Chronic Sinusitis
Yo Kimura, Hidekazu Furuse, Shin-ichi Okazaki and Ken-iti Isii
(Yamagata prefectural hospital)
Teruo Kiren
(Kiren ENT clinic)
Tomoo Watanabe
(Yamagata university school of medicine)
Twenty-six adult cases of acute exacerbation of chronic otitis media (COM) and twenty cases of acute exacerbation of chronic sinusitis (CS) were treated by Levofloxacin (LVFX) 400 mg a day in two divided portions. The clinical efficacy rates were 84.6％ for COM and 85％ for CS. Bacteriolgical therapeutic failures in treatment were observed in four COM and three CS patients. Adverse response and abnormal laboratory findings were not observed. LVFX was more effective when given at 400 mg a day in two divided portions.
Key words : Levofloxacin
(LVFX) 400 mg in two divided portions, Chronic Otitis Media, Chronic Sinusitis