PRACTICA OTO-RHINO-LARYNGOLOGICA

Vol. 99  No.   August   2006


A Case Report of Tonsillectomy with 
von Willebrand's Disease

Sachie Kawaguchi, Susumu Araki, Akira Hagiwara and Mamoru Suzuki
(Tokyo Medical University)
Tsuyoshi Takenouchi
(Tokyo Medical University Hachioji Medical Center)
Hideo Takagi
(Kousei Hospital)
Hitoshi Inoue
(Inoue ENT Clinic)

     von Willebrand's disease (vWD) is a frequent hereditary bleeding disorder due to a quantitative and/or qualitative deficiency of von Willebrand's factor (vWF). When surgery is considered coagulant therapies must be planned. There are several coagulant therapies. Factor VIII concentrates that contain von Willebrand's factor are most commonly used.
We report a patient with von Willebrand's disease who underwent tonsillectomy. The patient was a 29 year old man diagnosed as having von Willebrand's disease at 7 year old. He had previously demonstrated massive hemorrhage of the liver following a fine needle biopsy. We selected the therapy using the factor VIII concentrates containing von Willebrand's factor. Factor VIII concentrates containing von Willebrand's factor were administered preoperatively and postoperatively for 6 days. Bleeding was successfully controlled during and after tonsillectomy.


Key words :
tonsillectomy, von Willebrand's disease, factor VIII


第99巻8号 目次   Vol.99 No.8 contents